Table 2.

The identification of potential biomarkers in tissue level based on GC-MS.

Differential metabolites	m/z	RT	VIP	Fold change	p
Cancer tissue and paracarcinoma tissue
L-Lactic acid	318.0358	7.31	1.15	2.87	1.15E-10
2,3-Butanediol	116.0217	7.78	1.16	0.19	9.97E-06
3-Hydroxybutyric acid	373.0875	8.94	1.26	3.07	2.43E-16
allo-Inositol	405.1945	19.73	1.07	0.49	9.11E-09
Cholesterol	75.0181	27.94	1.06	0.39	1.12E-08
Allose	97.0683	17.98	1.21	4.02	7.61E-15
chiro-Inositol	381.1673	19.73	1.05	0.51	5.93E-08
d-Mannose	138.0889	17.98	1.23	5.89	6.43E-16
Heptadecanoic acid	146.0376	20.24	1.01	0.40	3.63E-08
Inositol	391.1874	19.73	1.12	0.48	1.25E-08
Malic acid	233.0896	13.2	1.05	0.09	1.40E-09
Muco-inositol	407.1886	19.73	1.01	0.53	6.86E-08
myo-Inositol	164.0926	19.76	1.24	9.40	7.65E-21
Oleic acid	117.0078	20.24	1.02	0.39	6.86E-08
Pentasiloxane	354.04859	8.92	1.26	2.94	1.05E-11
scyllo-Inositol	365.1554	19.73	1.08	0.48	1.01E-08
Stearic acid	116.0083	20.24	1.01	0.40	1.11E-07
Preoperative and postoperative serum
Stearic acid	298.2655	21.19	1.38	1.91	1.35E-02
3-Hydroxybutyric acid	86.0744	8.93	2.13	5.99	2.90E-02
9,12-Octadecadienoic acid	264.2632	20.98	2.24	3.63	6.28E-03
Cholestane-3,5-diol	329.3586	28.00	1.35	2.58	1.40E-02
Cholesterol	340.3024	20.98	2.16	3.50	4.01E-04
Glucose	96.0857	20.96	2.12	3.31	1.49E-02
elaidic acid	339.2998	20.97	2.16	3.17	8.60E-03
γ-Tocopherol	504.4245	27.86	1.58	2.35	8.40E-03
L-5-Oxoproline	258.0370	13.73	1.92	4.68	2.11E-03
Oleic acid	138.1276	20.96	2.19	3.51	1.31E-02
Palmitic acid	285.2381	19.40	1.44	2.04	1.60E-02
trans-13-Octadecenoic acid	84.0748	20.97	2.11	3.10	1.69E-02
Xanthotoxin	356.3373	21.18	1.06	1.78	1.33E-02