Table 3.
Result from ingenuity pathway analysis with MetaboAnalyst 5.0.
| Pathway name | Match status | p | -log(p) | FDR | Impact |
|---|---|---|---|---|---|
| Cancer tissue and paracarcinoma tissue | |||||
| Biosynthesis of unsaturated fatty acids | 2/36 | 0.025294 | 1.579 | 1 | 0 |
| Synthesis and degradation of ketone bodies | 1/5 | 0.035028 | 1.4556 | 1 | 0 |
| Ascorbate and aldarate metabolism | 1/8 | 0.055506 | 1.2557 | 1 | 0 |
| Butanoate metabolism | 1/15 | 0.10176 | 0.99242 | 1 | 0 |
| Pyruvate metabolism | 1/22 | 0.14595 | 0.83581 | 1 | 0 |
| Glycolysis/gluconeogenesis | 1/26 | 0.1703 | 0.76879 | 1 | 0 |
| Galactose metabolism | 1/27 | 0.17629 | 0.75378 | 1 | 0 |
| Phosphatidylinositol signaling system | 1/28 | 0.18224 | 0.73936 | 1 | 0.03736 |
| Inositol phosphate metabolism | 1/30 | 0.19402 | 0.71216 | 1 | 0.12939 |
| Steroid biosynthesis | 1/42 | 0.26153 | 0.58248 | 1 | 0.0282 |
| Primary bile acid biosynthesis | 1/46 | 0.28286 | 0.54843 | 1 | 0.05065 |
| Steroid hormone biosynthesis | 1/85 | 0.46338 | 0.33406 | 1 | 0.00528 |
| Preoperative and postoperative serum | |||||
| Biosynthesis of unsaturated fatty acids | 4/36 | 7.2193E-05 | 4.1415 | 0.0060643 | 0 |
| Synthesis and degradation of ketone bodies | 1/5 | 0.035028 | 1.4556 | 0.98079 | 0 |
| Linoleic acid metabolism | 1/5 | 0.035028 | 1.4556 | 0.98079 | 1 |
| Butanoate metabolism | 1/15 | 0.10176 | 0.99242 | 1 | 0 |
| Glycolysis/gluconeogenesis | 1/26 | 0.1703 | 0.76879 | 1 | 2.10E-04 |
| Glutathione metabolism | 1/28 | 0.18224 | 0.73936 | 1 | 0.00709 |
| Fatty acid elongation | 1/39 | 0.24515 | 0.61057 | 1 | 0 |
| Fatty acid degradation | 1/39 | 0.24515 | 0.61057 | 1 | 0 |
| Steroid biosynthesis | 1/42 | 0.26153 | 0.58248 | 1 | 0.0282 |
| Primary bile acid biosynthesis | 1/46 | 0.28286 | 0.54843 | 1 | 0.05065 |
| Fatty acid biosynthesis | 1/47 | 0.2881 | 0.54045 | 1 | 0.01473 |
| Steroid hormone biosynthesis | 1/85 | 0.46338 | 0.33406 | 1 | 0.00528 |
| Biosynthesis of unsaturated fatty acids | 4/36 | 7.2193E-05 | 4.1415 | 0.0060643 | 0 |
| Synthesis and degradation of ketone bodies | 1/5 | 0.035028 | 1.4556 | 0.98079 | 0 |
| Linoleic acid metabolism | 1/5 | 0.035028 | 1.4556 | 0.98079 | 1 |