. Author manuscript; available in PMC: 2022 Oct 1.

Published in final edited form as: Am J Ophthalmol. 2021 Jun 5;230:156–165. doi: 10.1016/j.ajo.2021.05.019

Table 2:

Mean predicted values of asymmetry, OCTA, and OCT parameters by diagnosis.

	Healthy^a	Suspect^a	POAG ^a
	Healthy^a	Suspect^a	Mild	Moderate	Severe	Any
Asymmetry Parameters
hdVAD	0.018 (0.017)	0.020 (0.018)	0.034 (0.025)^*	0.043 (0.036)^*	0.031 (0.027)^*	0.036 (0.029)^*
qdVAD	0.025 (0.024)	0.029 (0.028)	0.037 (0.030)^*	0.059 (0.047)^*	0.043 (0.035)	0.046 (0.038)^*
qdRNFL	13.5 (10.1)	14.9 (16.7)	13.8 (14.4)	15.4 (13.7)	12.7 (8.7)	13.9 (12.6)
VAD Parameters
gVAD	0.348 (0.043)	0.343 (0.049)	0.292 (0.060)^*	0.267 (0.062)^*	0.231 (0.071)^*	0.264 (0.070)^*
Superior Hemiretinal VAD	0.444 (0.035)	0.440 (0.042)	0.401 (0.055)^*	0.376 (0.059)^*	0.331 (0.082)^*	0.370 (0.073)^*
Inferior Hemiretinal VAD	0.436 (0.029)	0.431 (0.040)	0.386 (0.055)^*	0.350 (0.075)^*	0.310 (0.079)^*	0.349 (0.076)^*
Superior Quadrant VAD	0.471 (0.038)	0.458 (0.047)^*	0.420 (0.063)^*	0.384 (0.072)^*	0.331 (0.090)^*	0.379 (0.085)^*
Inferior Quadrant VAD	0.483 (0.029)	0.474 (0.043)^*	0.429 (0.058)^*	0.376 (0.096)^*	0.324 (0.092)^*	0.377 (0.093)^*
RNFL Parameters
gRNFL	92.2 (10.6)	88.2 (11.0)^*	78.2 (10.4)^*	73.3 (10.9)^*	68.1 (11.4)^*	73.7 (11.6)^*
Superior Quadrant RNFL	115.0 (16.6)	106.6 (17.831)^*	96.2 (18.6)^*	85.7 (18.7)^*	80.1 (16.9)^*	88.3 (19.3)^*
Inferior Quadrant RNFL	122.5 (18.3)	112.8 (21.5)^*	95.0 (20.3)^*	86.1 (24.7)^*	73.5 (17.7)^*	85.9 (22.6)^*
Visual Field Parameters
Visual Field Mean Deviation	−0.94 (2.67)	−1.39 (2.27)	−1.49 (3.38)	−5.88 (5.64)^*	−11.25 (8.67)^*	−6.17 (7.53)^*
Pattern Standard Deviation	2.28 (1.66)	2.21 (1.61)	2.06 (0.89)	5.13 (3.22)^*	7.11 (3.57)^*	4.69 (3.50)^*

Data listed as mean (standard deviation).

Statistically significantly different (P < 0.05) than healthy, as determined from age-adjusted multivariable linear regression of ocular parameter on diagnostic groups.

Abbreviations: OCTA=optical coherence tomography angiography; OCT=optical coherence tomography; POAG=primary open angle glaucoma; hdVAD=superior and inferior hemiretinal absolute difference in vessel area density; qdVAD=superior and inferior quadrant absolute difference in vessel area density; qdRNFL=superior and inferior quadrant absolute difference in retinal nerve fiber layer thickness; VAD=vessel area density; gVAD=global vessel area density; RNFL=retinal fiber layer thickness; gRNFL=average global retinal nerve fiber layer thickness.