Table 2.
Toxicities and complications attributed to or associated with ablative radiation
| Ablative Radiation | N (%) | Resection | N (%) |
|---|---|---|---|
| Patients with any toxicity/complicationa | 26 (25.0) | Patients with any complication | 59 (56.2) |
| Summary of toxicities/complications b | Worst complication grade d | ||
| Dyspepsia | 1 (1.0) | Grade 1 (no intervention) | 8 (7.6) |
| Gastric or duodenal ulcer | 1 (1.0) | Grade 2 (pharmacologic intervention only) | 21 (20.0) |
| Vertebral body fracture | 3 (2.9) | Grade 3 (intervention requiring anesthesia) | 22 (21.0) |
| Upper gastrointestinal bleeding | 6 (5.8) | Grade 4 (requiring ICU care) | 6 (5.7) |
| Duodenal stenosis | 3 (2.9) | Grade 5 (death within 90-days) | 2 (1.9) |
| Biliary obstruction | 4 (3.8) | ||
| Complication with biliary stent | 11(10.6) | ||
| Death within 90-daysc | 5 (4.8) |
ICU = intensive care unit
a
Patients may have more than one toxicity or complication listed
b
Radiation Therapy Oncology Group (RTOG) and European Organization for Research and Treatment of Cancer (EORTC) criteria
c
None directly attributed to ablative radiation
d
Clavien-Dindo classification