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A schematic diagram of a part of the tick gut. The diagram shows the occurrence of the peritrophic matrix (PM) and the possible location of the dityrosine network (DTN) in the gut of a fed I. scapularis tick. The Lyme disease pathogens exist in the gut lumen and are surrounded by the PM of an infected I. scapularis tick. This figure was created using BioRender (https://biorender.com/).
