Table 2.
Ureteric bud / collecting duct lineage genes are expressed in distal tubular cells. Shown is the percentage of cells expressing ureteric bud / collecting duct (ub/cd) lineage marker genes Calb1, Mal, Mecom and Wfdc2 for cells from immature and mature distal and proximal tubular clusters, and also from the ub/cd cluster.
| Cluster | Calb1 | Mal | Mecom | Wfdc2 |
|---|---|---|---|---|
| i_tubular_prox | 3.1 | 3.1 | 3.1 | 48.4 |
| m_tubular_prox | 1.6 | 1.6 | 4.7 | 42.2 |
| i_tubular_dist | 26.4 | 86.8 | 92.5 | 98.1 |
| m_tubular_dist | 14.6 | 91.7 | 87.5 | 100.0 |
| ub/collecting-duct | 83.6 | 52.0 | 71.0 | 99.7 |
In the tubular distal lineage, in contrast to the proximal lineage, a significant fraction of cells expresses these four ureteric bud/collecting duct marker genes.