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. Author manuscript; available in PMC: 2022 Nov 15.
Published in final edited form as: J Control Release. 2021 Oct 12;339:484–497. doi: 10.1016/j.jconrel.2021.10.007

Figure 8.

Figure 8.

The effect of the ProGel-Dex treatment in the MIA OA-like pain mouse model. (a) Histology of knee joint sections photographed at 400× magnification. Upper panel, H&E-stained sections; Lower panel, Safranin-O-stained sections. Black arrow: synovial cell lining hyperplasia; red arrow: pannus formation; blue arrow: mononuclear cell infiltration; green arrow: cellular infiltration in cartilage. (b) The sum of histology scores of H&E-stained sections from MIA mice evaluated and scored by a professional pathologist. (c) Static weight distribution of MIA mice. T1 = pre-induction; T2 = pre-injection. *, P ≤ 0.05; **, P ≤ 0.01.