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. 2021 Nov 17;11:22386. doi: 10.1038/s41598-021-01899-8

Table 5.

Minimal clinically important difference.

OSDI decrease by > 10 points FBUT increase by > 5 s
0 to 3 months 0 to 6 months 0 to 3 months 0 to 6 months
Blephasteam 58% 50% 24% 22%
TheraPearl 50% 44% 32% 27%
Between treatment P-value 0.61 0.79 0.68 0.90

OSDI ocular surface disease index, FBUT fluorescein breakup time.