Table 2.
Stewardship and safety measures
| Overall, |
ICU, |
General, |
Medical, |
Surgical, |
||||||
|---|---|---|---|---|---|---|---|---|---|---|
| n = 44 | n = 32 | n = 12 | n = 22 | n = 22 | ||||||
| Antibiotic stewardship errors | 18 | (40.9) | 14 | (43.8) | 4 | (33.3) | 7 | (31.8) | 11 | (50.0) |
| Inappropriate choice | 11 | (25.0) | 7 | (21.8) | 2 | (16.6) | 6 | (27.2) | 3 | (13.6) |
| No prior culture | 11 | (25.0) | 7 | (21.9) | 4 | (33.3) | 0 | (0.0) | 11 | (50.0) |
| Not treated with combination therapy | 11 | (25.0) | 6 | (18.8) | 5 | (41.7) | 5 | (22.7) | 6 | (27.2) |
| Failed to de-escalate | 2 | of 9 | 1 | of 8 | 1 | of 1 | 1 | of 5 | 1 | of 4 |
| Safety errors | 29 | (65.9) | 18 | (56.3) | 11 | (91.7) | 11 | (0.50) | 18 | (81.8) |
| Loading dose error | 12 | (27.3) | 6 | (18.8) | 6 | (50.0) | 3 | (13.6) | 9 | (40.9) |
| Incorrect loading dose | 4 | (9.1) | 3 | (9.4) | 1 | (8.3) | 0 | (0.0) | 4 | (18.2) |
| Loading dose not prescribed | 8 | (18.2) | 3 | (9.4) | 5 | (41.7) | 3 | (13.6) | 5 | (22.7) |
| Maintenance dose error | 10 | (22.7) | 8 | (25.0) | 2 | (16.7) | 5 | (22.7) | 5 | (22.7) |
| Incorrect maintenance dose | 7 | (15.9) | 3 | (9.4) | 0 | (0.0) | 2 | (9.1) | 1 | (4.5) |
| Initial maintenance dose not according to GFR | 3 | (6.8) | 5 | (15.6) | 2 | (16.7) | 3 | (13.6) | 4 | (18.2) |
| Not dosed according to either local guideline | 16 | (36.4) | 10 | (31.3) | 6 | (50.0) | 5 | (22.7) | 11 | (50.0) |
| Renal function not monitored | 16 | (36.4) | 6 | (18.8) | 10 | (83.3) | 5 | (22.7) | 11 | (50.0) |
| Maintenance dose not adjusted after change in GFR | 6 | of 15 | 6 | of 13 | 0 | of 2 | 3 | of 8 | 3 | of 7 |
| Total errors per patient, median (IQR) | 1 | (1–2) | 1 | (0–2) | 2 | (1–3) | 1 | (0–2) | 2 | (1–3) |
| 0 | 10 | (22.7) | 9 | (28.1) | 1 | (8.3) | 7 | (31.8) | 3 | (13.6) |
| 1 | 16 | (36.4) | 12 | (37.5) | 4 | (33.3) | 9 | (40.9) | 7 | (31.8) |
| 2 | 2 | (20.5) | 6 | (18.6) | 3 | (25.0) | 4 | (18.2) | 5 | (22.7) |
| 3 | 4 | (9.1) | 3 | (9.4) | 1 | (8.3) | 2 | (9.1) | 2 | (9.1) |
| 4 | 5 | (11.4) | 2 | (6.3) | 3 | (25.0) | 0 | (0.0) | 5 | (22.7) |
Values are shown as n (%) unless stated otherwise.
GFR, glomerular filtration rate.