Figure 2.

Harms and benefits associated with different screening strategies among women who learned at age 40 years about a positive first-degree family member with breast cancer. Estimates of Model E per 1000 women screened. The underlined strategies are the commonly followed guidelines of the United States Preventive Services Task Force (USPSTF), the American Cancer Society (ACS), and the American College of Radiology (ACR). The figure shows (A) life-years gained vs overdiagnosed breast cancers; (B) breast cancer deaths averted vs overdiagnosed breast cancers; (C) life-years gained vs false-positive mammograms; and (D) breast cancer deaths averted vs false-positive mammograms.