Table 2.
Screening guidelinea | Screening strategy | Screens, No. | LYGb | BC deaths avertedb | Overdiagnoses | False positives | LYG/screens | LYG/ overdiagnoses | BC deaths averted/false positives |
---|---|---|---|---|---|---|---|---|---|
USPSTF | Bi 50-74 y | 11 182 | 118 | 6.7 | 14.5 | 920 | 0.0106 | 8.14 | 0.0072 |
ACR | An 40-74 y | 31 083 | 192 | 9.6 | 21.5 | 2910 | 0.0062 | 8.94 | 0.0033 |
ACS |
An 45-54, Bi 55-74 |
17 984 | 151 | 7.7 | 16.5 | 1666 | 0.0084 | 9.16 | 0.0046 |
We used age 74 years as the age of the last possible screen for comparability across screening strategies for all analyses. ACR = American College of Radiology; ACS = American Cancer Society; An = annual; BC = breast cancer; Bi = biennial; LYG = life-years gained; USPSTF = United States Preventive Services Task Force.
The LYG and BC deaths averted are relative to the life-years and BC deaths of women at the same level of age-specific BC risk who are never screened.