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. 2020 Jul 30;37(2):202–212. doi: 10.1093/bioinformatics/btaa690

Table 1.

Transcription factors with Z-score greater than 1 based on 3000 cluster proposals

Gene name zg Associated cell type Citation
Creb3l3 34.20
Tfeb 13.37
Rhox6 10.15
Elf5 9.45 Extraembryonic ectoderm Latos et al. (2015)
Gata1 8.77 Primitive erythrocyte Baron (2013)
Pou5f1 8.38 Epiblast, primitive streak Mulas et al. (2018)
Sox17 5.61 Endoderm Viotti et al. (2014)
Nr0b1 5.58
Hoxb1 4.54 Mesoderm Carapuço et al. (2005)
Foxf1 3.36 Lateral plate mesoderm Mahlapuu et al. (2001)
Gata2 3.27 Extraembryonic mesoderm Silver and Palis (1997)
Prdm6 3.12
Bcl11a 2.99
Foxa2 2.70 Anterior visceral endoderm, anterior primitive streak Perea-Gomez et al. (2001) and Arnold et al. (2008)
Gsc 2.67 Anterior primitive streak Lewis et al. (2007)
Hand1 2.57 Posterior mesoderm, lateral plate mesoderm Riley et al. (1998)
Ascl2 2.52 Ectoplacental cone Simmons and Cross (2005)
Mesp1 2.46 Posterior primitive streak Arnold and Robertson (2009)
Hoxa1 2.44 Mesoderm Carapuço et al. (2005)
Nanog 2.24 Epiblast Mulas et al. (2018)
Zfp42 2.14 Extraembryonic ectoderm Pelton et al. (2002)
Cdx1 2.12 Paraxial mesoderm van den Akker et al. (2002)
Runx1 1.82
Hoxb2 1.73 Mesoderm Carapuço et al. (2005)
Id2 1.51 Extraembryonic ectoderm Jen et al. (1997)
Tbx3 1.31
Pitx2 1.20

Note: For each transcription factor, we list the associated cell type from early mouse gastrulation.