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. 2021 Nov 17;12:6655. doi: 10.1038/s41467-021-26821-8

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — a Quantification of TCR ITH by Jaccard index (JI), a metric representing the proportion of shared T-cell clonotypes between two samples in 10 SCLC patients with multiregion TCR sequencing data. b Proportions of T-cell clonotypes detected in all regions (shared, blue), in 2/3 (brown) and restricted to a single region (red) from the same tumors in 10 SCLC patients with multiregion TCR sequencing data. Patient ID: purple = alive; green = deceased. Source data are provided as a Source Data file.