Table 4.
Least square geometric means of plasma C-peptide and HbA1c level by diabetes duration in NHS and HPFSa
| Diabetes duration | C-peptide |
HbA1c |
||
|---|---|---|---|---|
| No. | Least square geometric mean (95% CI), ng/ml | No. | Least square geometric mean% (95% CI) | |
| No diabetes | 9710 | 2.54 (2.26 to 2.85) | 7714 | 5.55 (5.43 to 5.68) |
| 0-2.0 y | 75 | 3.32 (2.81 to 3.93) | 201 | 7.18 (7.02 to 7.34) |
| 2.1-4.0 y | 46 | 2.67 (2.20 to 3.24) | 160 | 7.15 (6.99 to 7.32) |
| 4.1-8.0 y | 95 | 2.85 (2.43 to 3.34) | 275 | 7.69 (7.55 to 7.84) |
| 8.1-10.0 y | 96 | 1.73 (1.48 to 2.03) | 184 | 7.65 (7.49 to 7.81) |
| 10.1-15.0 y | 34 | 1.99 (1.60 to 2.46) | 209 | 7.92 (7.77 to 8.08) |
| ≥ 15.0 y | 34 | 2.09 (1.68 to 2.59) | 225 | 7.21 (7.06 to 7.36) |
a
Data were combined from 2 cohorts. Multiple linear regression adjusted for age at blood draw, aspirin/NSAIDs use, presence of chronic diseases or conditions (hypercholesterinemia, hypertension, cancer, osteoporosis, rheumatoid arthritis, stroke, and myocardial infarction), physical activity (continuous), current smoking status (yes, no), case-control status, sex, and body mass index (continuous). CI = confidence interval; HPFS; Health Professionals Follow-up Study; NHS = Nurses’ Health Study.