Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Nov 4;12:760999. doi: 10.3389/fimmu.2021.760999

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2021 Ren, Yan, Wang, Zhang, Li, Xiong, Jing, Li, Zhao, Xiong, Wu and Zhong

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

The protective effects of hID2 on colitis was not dependent on the gut microbiota. Fresh faeces were collected from mice on Day 8, and DNA was extracted for 16S rDNA sequencing. The alpha diversity index of the gut microbiota with the (A) Chao index and (B) phylogenetic diversity (Pd) index at the OTU level. (C) Rarefaction curves of the observed richness index (Sobs) at the OTU level. (D) The rank of distance on the OTU level of each group. (E) PCA of the intestinal microbiota at the OTU level in mice. PC1 and PC2 exhibited 12.47% and 9.28% of the variation, respectively. (F) The Firmicutes/Bacteroidetes (F/B) ratio at the phylum level. The ratio of F/B results is presented as the mean ± SEM. n=6 for each treatment. ^* p < 0.05, ^** p < 0.01, ^*** p < 0.001.