Table 3.
Comparison of performance in the multimodal ACNN model and preoperative CNB for predicting four-classification molecular subtypes of breast cancers.
Methods | Datasets | AUC | Sensitivity (%) | Specificity (%) | Accuracy (%) |
---|---|---|---|---|---|
Multimodal ACNN model | Internal validation cohort (n=37) | 0.89 | 84.87 | 82.47 | 83.73 |
Test cohort A (n=42) | 0.92 | 83.00 | 81.35 | 83.33 | |
Test cohort B (n=24) | 0.99 | 89.62 | 76.27 | 83.33 | |
Preoperative CNB | Internal validation cohort (n=37) | 0.67 | 51.56 | 49.70 | 64.86 |
Test cohort A (n=42) | 0.74 | 61.11 | 70.93 | 66.67 | |
Test cohort B (n=24) | 0.82 | 49.66 | 63.54 | 62.50 |
Note. —The multimodal ACNN model was trained and tested with greyscale US and CDFI as well as SWE images.
ACNN, assembled convolutional neural network; AUC, area under the receiver operating characteristic curve; CNB, core needle biopsy.