TABLE 2.

Performances of Fecal Calprotectin to Detect Endoscopic Ulcerations According to Crohn’s Disease Location (Ileal vs Colonic or Ileocolonic)

	No. patients	Cutoff value	AUC	Se	Spe	PPV	NPV	Accuracy
Ileal CD	40	200 µg/g	0.81 (0.68–0.94)	75.0% (47.6–92.7)	87.5% (67.6–97.3)	80.0% (51.9–95.7)	80.8% (63.9–95.5)	82.5%
Ileal CD	40	250 µg/g	0.78 (0.64–0.92)	68.8% (41.3–89.0)	87.5% (67.6–97.3)	78.6% (49.2–95.3)	80.8% (60.6–93.4)	80.0%
Colonic or ileocolonic CD	83	250 µg/g	0.79 (0.70–0.88)	84.1% (69.9–93.4)	74.4% (57.9–87.0)	78.7% (64.3–89.3)	80.6% (64.0–91.8)	79.5%
P a			ns	ns	ns	ns	ns	ns

Abbreviations: Se, sensitivity, Spe, specificity; ns: nonsignificant (P > 0.05). _aComparisons between fecal calprotectin >200 µg/g in ileal CD vs fecal calprotectin >250 µg/g in colonic or ileocolonic CD and between fecal calprotectin >250 µg/g in ileal CD vs colonic or ileocolonic CD.