TABLE 3.

Performances of Fecal Calprotectin to Detect the Presence of Endoscopic Lesions According to Crohn’s Disease Location (Ileal vs Colonic or Ileocolonic)

	No. patients	Cutoff value	AUC	Se	Spe	PPV	NPV	Accuracy
Ileal CD	40	100 µg/g	0.85 (0.73–0.96)	87.0% (66.4–97.2)	82.4% (56.6–96.2)	87.0% (66.4–97.2)	82.4% (56.6–96.2)	85.0% (73.9–96.1)
Colonic or ileocolonic CD	83	100 µg/g	0.79 (0.68–0.90)	84.4% (73.1–92.2)	73.7% (48.8–90.9)	91.5% (81.3–97.2)	58.3% (36.6–77.9)	81.9% (73.6–90.2)
P			ns	ns	ns	ns	ns	ns

Abbreviations: Se, sensitivity; Spe, specificity; ns, nonsignificant (P > 0.05). _aComparisons between fecal calprotectin >200 µg/g in ileal CD vs fecal calprotectin >250 µg/g in colonic or ileocolonic CD and between fecal calprotectin >250 µg/g in ileal CD vs colonic or ileocolonic CD.