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. 2021 Nov 4;12:756415. doi: 10.3389/fphar.2021.756415

TABLE 3.

PDVs and their contact variants in the closed-PD model ^a .

PDV		Contacts
Variant	Syndrome	Variant	Syndrome	Signif
^IS6A⁴¹³E	LQT3	^IVS6N¹⁷⁷⁴D	LQT3	NP
S	NS	S	BrS1	NP
T	A, LQT3,BrS1	Y	NS	CIP
^IIIS6N¹⁴⁶³K	NP	^IIS5S⁸³⁵L	BrS1	NP
^IIIS6N¹⁴⁶³K	NP	A	BrS1	VUS
^IIIS6F¹⁴⁶⁵L	LQT3	^IVS6I¹⁷⁶⁸V	BrS1, LQT3	P
^IIIS6I¹⁴⁶⁹F	NP	^IVS6I¹⁷⁶⁸V	BrS1, LQT3	P
		^IVS6L¹⁷⁷²P	BrS1	VUS
		V	LQT3	NP
^IVS6M¹⁷⁶⁶I	CVP, BrS1	^IVS6G¹⁶⁶¹R	BrS1	NP, CIP
K	NP, BrS1, SSS
V	BrS1
T	HCM
L	LQT3

^a

Contacts in the cryo-EM structure (Table 1) are not shown.