. 2021 Nov 4;12:756415. doi: 10.3389/fphar.2021.756415

TABLE 4.

PDVs and their contacts in activated VSDs^a.

PDVs		Contacts
Variant^b	Syndrome^c	Mutation	Syndrome^d	Significance	^e	^f
^IS1M¹³⁸I	AF	^IS4T²²⁹S	BrS1	VUS		S
T	DCM¹	^IS4-S5V²³²I	A, BrS1, CVP	CIP		S
^IS1I¹⁴¹N	BrS1	^IS4T²²⁹S	BrS1	VUS		S
F	NS	^IS4R²²⁵Q	BrS1, LQT3, More	CIP		S
		W	BrS1, LQT3, More	P/LP		S
		^IS4A²²⁶D	BrS1	VUS		S
		V	BrS1, LQT3, More	CIP
		^IS4V²³²I	A, BrS1, CVP	CIP
^IS2R¹⁷⁹P	BrS1	^IS1L¹²⁸P	BrS1	VUS	4
Q	BrS1	^IS2-S3T¹⁸⁷S	BrS1	VUS
		I	BrS1	NP
		A	BrS1, CA	CIP
^IS2-S3T¹⁸⁷S	BrS1	^IS2R¹⁷⁹P	BrS1	VUS	4
I	BrS1, NP	Q	BrS1	VUS
A	BrS1			VUS
^IS3D¹⁹⁷G	BrS1	^IS2K¹⁷⁵D	BrS1	NP
H	BrS1	^IS2E¹⁷¹G	BrS1	VUS
Y	DCM
^IIS3E⁷⁹⁵K	BrS1	^IIS4L⁸⁰⁷P	BrS1, NP	VUS		S
^IIS4-S5L⁸²⁵P	BrS1	^IIS4F⁸¹⁶L	A	VUS		S
		Y	LQT3	NP		S
		^IIIS5V¹³⁴⁰L	CVP	VUS
		I	NP, BrS1, A	VUS
^IIS5I⁸⁴⁸F	A,BrS1, LQT3¹	^IS4A²²⁶V	BrS1, LQT3, More	CIP		S
		D	BrS1	VUS		S
		^IS4I²³⁰T				S
^IIIS1A¹²²¹V	A, BrS1	^IIIS2L¹²³⁹P	BrS1	NP
^IIIS4R¹³⁰⁶L	CVP	^IIIS2D¹²⁴³E	BrS1	VUS		S
H	NP, BrS1	NG	BrS1, More	VUS		S
C	A	^IIIS2E¹²²⁵K	BrS1	VUS		S
S	BrS1		LQT3, BrS1, A	VUS		S
^IIIS4R¹³¹⁶L	BrS1	^IIIS1E¹²⁰⁸K	A, NP	VUS		S
Q	BrS1
^IVS2E¹⁵⁷⁴K	BrS1^1,3	^IVS1I¹⁵³⁴S	LQT3	VUS		S
^IVS2C¹⁵⁷⁵Y	A, BrS1	^IVS3F¹⁵⁹⁶I	LQT3, BrS1, More	VUS
S	A	^IVS3F¹⁵⁹⁶I	LQT3, BrS1, More	VUS
^IVS3N¹⁵⁹²Y	BrS1	^IVS4R¹⁶³⁸P	NP	LP
^IVS4-S5I¹⁶⁴³L	NP	^IVS3I¹⁶³⁷T	NS	VUS

^a-e footnotes to Table 1.