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. 2021 Nov 4;12:756415. doi: 10.3389/fphar.2021.756415

TABLE 8.

Domain distribution of disease variants.

Location State BrS1 LQT3 Arrythmias Other diseases
PDV Contacts PDV Contacts PDV Contacts PDV Contacts
PD Inactivated a 21 30 6 10 3 6 10 7
Open b 2 3 1
Closed b 6 3 1
VSD1 Activated a 10 14 2 3 2
Resting c 3 5 1 2 1
VSD2 Activated a 3 7 1 3 1 2 1
Resting c 4 2 2 2
VSD3 Activated a 5 5 1 1 1 1
Resting c 1
VSD4 Activated a 4 2 2 1 1
Resting c 3 1
Total 46 78 8 30 4 11 17 15

a-c See footnotes to Table 7.