Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Schematic representation of U-to-Ψ isomerization and additional N1 methylation. Ψ is a rotational isomer of uridine, in which the N-C glycosidic bond is substituted with the C-C bond. The isomerization reaction also creates an extra hydrogen bond donor (-N1H). Ψ can be further methylated at the N1 position by Nep1 (an N1-specific Ψ methyltransferase) to generate N-methyl-Ψ. d, hydrogen bond donor; a, hydrogen bond acceptor.
