Fig. 2.

Predictive margin plots illustrating the regression results from (a) models 1.a-c and (b) models 2.a-c for the associations of obesity metrics (BMI, WHR and WC), as well as age, with gray matter cerebral blood flow

Data are presented across ± 3 standard deviations of the cohort distribution. (A) Models 1.a, 1.b, and 1.c: association of mean body mass index (BMI), waist-to-hip ratio (WHR), and waist circumference (WC) with gray matter cerebral blood flow (CBFGM [ml/100g/min]) adjusted for age and sex. (B) Models 2.a, 2.b, and 2.c: association of BMI, WHR, and WC with CBFGM fully adjusted for all corelates. Age associations taken from models (A) 1.b and (B) 2.b. Error bars represent the 95% CIs, shown at the mean and at ± 1, 2 and 3 standard deviations from the mean for each measure (BMI, WHR, WC and age).