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. 2021 Nov 4;12:760468. doi: 10.3389/fimmu.2021.760468

Figure 2.

Figure 2

Differential miR-let-7e-5p, miR-197-3p and miR-223-3p expression in serum exosomes from DR-TB patients and healthy subjects. Serum exosomes were isolated, miRNAs amplification was done by qPCR. The data were expressed as ΔCT, defined as the relative expression of each miRNA with respect to the endogenous control (mirR-145-5p). Box plots depict medians and quartiles. (A) DR-TB patients (n = 24) and (B) MDR-TB patients (n = 20) and healthy subjects (n = 16), p < 0.05, (TB vs. Control), DR, Drug Resistant; MDR, Multi Drug Resistant. Raw CT data were normalized, and expression differences between cases and controls were assessed by an unpaired two-samples Mann-Whitney test. Only statistical differences with p < 0.05 are shown.