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. 2021 Nov 4;11:736941. doi: 10.3389/fonc.2021.736941

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Copyright © 2021 Lin, Wei, Hu, Zhang, Wei, Qian and Zou

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Involvement of the Notch/STAT3 pathway in RBM8A-mediated GBM cell proliferation and invasion. (A) Cell proliferation were analyzed in A172 or T98G cells overexpressing RBM8A (OE) in the presence or absence of the γ-secretase inhibitor DAPT using the CCK8 assay. (B) Transwell analysis with or without DAPT. (C) Matrigel-Transwell analysis with or without DAPT. (D) Western blot analysis of Notch1, phospho-STAT3, total STAT3, and actin after incubation with or without DAPT. All micrographs are shown at a magnification of 200×.