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. 2021 Nov 4;11:736941. doi: 10.3389/fonc.2021.736941

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Copyright © 2021 Lin, Wei, Hu, Zhang, Wei, Qian and Zou

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effects of RBM8A reduction on GBM progression in vivo. (A) Nude mice were intracranially injected with U87-MG cells transformed with empty lentivirus (NC) or lentivirus encoding short hairpin RBM8A-KD1. At 6 weeks after injection, animals were examined by MRI. (B) Representative photomicrographs of tumor sections stained with hematoxylin-eosin (H&E). (C) Immunohistochemistry of tumor tissues stained with antibody against RBM8A. (D) Immunohistochemistry of tumor tissues stained with antibody against Notch1.