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. 2021 Nov 11;48:102185. doi: 10.1016/j.redox.2021.102185

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© 2021 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig. 7 — EGCG pretreatment upregulated AMPKα2 and improved redox equilibrium and mitochondrial function in the Dox-injured mouse myocardium. A Western blot bands showing total and phosphorylated AMPKα2 and ACC expression, NDUFB8 and UQCRC2 expression, and the relative intensities of p-AMPKα2/AMPKα2 and p-ACC/ACC expression in the mouse myocardium. B Relative intensities of NDUFB8 and UQCRC2 expression in the mouse myocardium. C The contents of α-KG and Suc in the mouse myocardium. D The ATP contents in the mouse myocardium. E DHE/MitoSOX probe-stained images and the relative fluorescence intensity of DHE/MitoSOX in the mouse myocardium. F The levels of GSH, GSSG, and the GSH/GSSG ratio in the mouse myocardium. G The MDA contents in the mouse myocardium. H The 4-HNE contents in the mouse myocardium. Values are mean ± SD from three individual experiments. NS, nonsignificant. *p < 0.05 compared with the indicated groups. **p < 0.01 compared with the indicated groups.

Fig. 7 — EGCG pretreatment upregulated AMPKα2 and improved redox equilibrium and mitochondrial function in the Dox-injured mouse myocardium. A Western blot bands showing total and phosphorylated AMPKα2 and ACC expression, NDUFB8 and UQCRC2 expression, and the relative intensities of p-AMPKα2/AMPKα2 and p-ACC/ACC expression in the mouse myocardium. B Relative intensities of NDUFB8 and UQCRC2 expression in the mouse myocardium. C The contents of α-KG and Suc in the mouse myocardium. D The ATP contents in the mouse myocardium. E DHE/MitoSOX probe-stained images and the relative fluorescence intensity of DHE/MitoSOX in the mouse myocardium. F The levels of GSH, GSSG, and the GSH/GSSG ratio in the mouse myocardium. G The MDA contents in the mouse myocardium. H The 4-HNE contents in the mouse myocardium. Values are mean ± SD from three individual experiments. NS, nonsignificant. *p < 0.05 compared with the indicated groups. **p < 0.01 compared with the indicated groups.