Table 1.
Clinical and pathological characteristics of the study population (n=1806 breast lesions).
| Variable | BC (n = 1806) | Variable | BC (n = 1806) |
|---|---|---|---|
| Age at diagnosis (years) | 62 ± 13 [26–95] | pN | |
| BMI | 26.7 ± 25.5 [14.2-46.1] | 0 | 1204 (70.2%) |
| Hormonal Status | 1 | 360 (21%) | |
| Fertile | 439 (24.3%) | 2 | 88 (5.1%) |
| Pregnancy | 2 (0.1%) | 3 | 63 (3.7%) |
| Menopause | 1347 (74.6%) | Biological portrait | |
| Replacement therapy | 18 (1%) | ER+/HER2- | 1368 (80.9%) |
| Type of surgery | ER+/HER2+ | 144 (8.5%) | |
| Conservative surgery | 1345 (74.5%) | ER-/HER2+ | 69 (4.1%) |
| Mastectomy | 461 (25.5%) | ER-/HER2- | 110 (6.5%) |
| Axillary dissection | PG | ||
| No | 1180 (65.3%) | Negative | 384 (21.3%) |
| Yes | 626 (34.7%) | Positive | 1422 (78.7%) |
| LNS biopsy | Ki67 | ||
| No | 316 (17.5%) | ≤ 14% | 1177 (65.2%) |
| Yes | 1490 (82.5%) | > 14% | 629 (34.8%) |
| Type of breast cancer | Radiotherapy | ||
| Microinvasive | 27 (1.5%) | No | 504 (28.1%) |
| Invasive | 1779 (98.5%) | Yes | 1288 (71.9%) |
| Histological type | Chemotherapy | ||
| Ductal | 1409 (78%) | No | 1218 (68.2%) |
| Lobular | 278 (15.4%) | Yes | 567 (31.8%) |
| Others | 119 (6.6%) | Biological therapy | |
| Grading | No | 1487 (89.6%) | |
| I | 190 (10.6%) | Yes | 173 (10.4%) |
| II | 1133 (63.2%) | Hormonal therapy | |
| III | 469 (26.2%) | No | 307 (17.2%) |
| Lymphovascular invasion | Yes | 1476 (82.8%) | |
| No | 1053 (58.6%) | Exitus | |
| Yes | 744 (41.4%) | No | 1779 (98.0%) |
| Tumor dimension (mm) | 15 ± 9 [0-100] | Yes | 37 (2.0%) |
| pT | DM | ||
| X | 7 (0.4%) | No | 1700 (94.1%) |
| 1 | 1468 (81.3%) | Yes | 106 (5.9%) |
| 2 | 305 (16.9%) | Time to DM (months) | 25 ± 25 [0-60] |
| 3 | 12 (0.6%) | LRR | |
| 4 | 14 (0.8%) | No | 1715 (92.6%) |
| Yes | 91 (7.4%) | ||
| Time to LRR (months) | 25 ± 25 [0-60] |
BC, breast cancer; BMI, body mass index; ER, estrogen receptor; HER2, human epidermal growth factor receptor 2; PG, progesterone receptor; DM, distant metastasis; LRR, locoregional recurrence.
Data are expressed as mean ± standard deviation or total numbers; range and frequency distribution are shown within square and round parentheses, respectively.