Figure 6.

Effect of AuNPs on the memory response of monocytes primed by live (H) pylori. CD14⁺ monocytes were exposed to medium or H. pylori (at MOI 0.2) for 24 h in the presence or absence of AuNPs (20 µg/mL, indicated by blue bars), then washed and rested for 6 days. After resting, cells were challenged with LPS (5 ng/mL) for 24 h, supernatants were collected and examined for the production of TNFα (A), IL-6 (B), IL-1Ra (C) and IL-10 (D). Values from individual donors are depicted concurrent with mean cytokine production. p values are indicated when < 0.05 for the comparisons between unprimed and primed groups and priming with and without NPs, n = 4. .