Skip to main content
. 2021 Nov 4;12:720345. doi: 10.3389/fphar.2021.720345

FIGURE 2.

FIGURE 2

Fluorescein angiography and optical coherence tomography (OCT) B-scans of a patient with subfoveal choroidal neovascularization secondary to neovascular age-related macular degeneration. (A) Baseline fluorescein angiography demonstrates the presence of a subfoveal type 1 choroidal neovascularization. (B) OCT B-scan at the diagnosis shows a hypereflective subfoveal lesion with intra- and sub-retinal accumulation of fluid (IRF and SRF). (C) OCT B-scan at 13-month follow-up after a total of eight IVT injections of ranibizumab demonstrates the persistence of IRF and SRF. Therefore, the patient was switched to monthly intravitreal brolucizumab (IVT-B). (D) OCT B-scan 1-month visit after the first IVT-B reveals the complete resolution of IRF and SRF with a reduction of the central subfield thickness from 354 to 233 µm. (E) OCT B-scan at 3-month visit after the third IVT-B shows a dry retina and no recurrences are observed. Furthermore, the visual acuity improved from 20/125 to 20/80.