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PDE-5 is involved in olfactory encoding in AWB neurons. (A,B) 0.01% IAA-induced calcium increases in AWB neurons were reduced in pde-5(nj49) mutants. (A) Representative traces. (B) Quantification of the maximumΔF/F0. n ≥ 10. (C,D) 1% IAA removal-induced calcium increases in AWB neurons were reduced in pde-5(nj49) mutants. (C) Representative traces. (D) Quantification of the maximumΔF/F0. n ≥ 11. Error bars: SEM. N.S., not significant, *P < 0.05, **P < 0.01.
