Table 2.

Linear regression model comparing the FBA metrics in HIV+ and HIV– individuals, with age and sex included as covariates.

ROI	HIV+	HIV–	Estimate	Std error	p-value	Effect size
FD
Right PLIC	0.601	0.614	−0.020	0.006	0.03	0.46
Left PLIC	0.610	0.619	−0.013	0.007	0.28	0.29
Left SCR	0.352	0.356	−0.004	0.003	0.70	0.27
Right SCR	0.352	0.355	−0.001	0.004	0.81	0.17
Right ICP	0.402	0.406	0.007	0.012	0.81	0.08
Left ICP	0.427	0.427	0.012	0.011	0.72	0.01
MCP	0.448	0.443	0.004	0.009	0.81	0.14
logFC
Right PLIC	−0.032	−0.007	−0.069	0.019	<0.001	0.30
Left PLIC	−0.028	−0.011	−0.067	0.019	<0.001	0.19
Left SCR	0.025	0.023	−0.043	0.019	0.03	0.03
Right SCR	0.026	0.029	−0.046	0.019	0.03	0.04
Right ICP	−0.017	0.017	−0.077	0.017	<0.001	0.43
Left ICP	−0.013	0.024	−0.075	0.016	<0.001	0.46
MCP	0.068	0.110	−0.094	0.021	<0.001	0.40
FDC
Right PLIC	0.585	0.617	−0.065	0.015	<0.001	0.45
Left PLIC	0.599	0.621	−0.059	0.015	<0.001	0.32
Left SCR	0.361	0.367	−0.023	0.009	0.02	0.15
Right SCR	0.362	0.368	−0.020	0.010	0.06	0.16
Right ICP	0.396	0.415	−0.022	0.129	0.11	0.36
Left ICP	0.420	0.434	−0.019	0.012	0.12	0.27
MCP	0.485	0.502	−0.043	0.016	0.02	0.24

Estimate is average difference between HIV+ and HIV– for which HIV– is taken as the reference group (two-tailed t-test, FDR corrected at the α = 0.05 significance level). PLIC, posterior limb of internal capsule; SCR, superior corona radiate; ICP, inferior cerebellar peduncle; MCP, middle cerebellar peduncle. Significant results are shown as bold. p-values are false discovery rate (FDR)-corrected.