Table 3.
Extracellular vesicle (EV) concentration and percentage [%] of Annexin V+ EV in patients with ST-elevation myocardial infarction (STEMI) with either normal-lightly (≥40 %) or moderately-severely (<40 %) reduced left ventricular ejection fraction (LVEF).
| Parameter | LVEF ≥ 40 % (n = 15) | LVEF <40 % (n = 4) | p-value |
|---|---|---|---|
| Total Annexin V+ EV/ml | 57,145 ± 10,360 | 82,498 ± 26,057 | 0.30 |
| CD61+ EV/ml | 7,499 ± 1,408 | 4,687 ± 645.6 | 0.33 |
| Caveolin-3+ EV/ml | 2,819 ± 776.6 | 8,992 ± 4,425 | 0.03 |
| CD45+ EV/ml | 300.0 ± 230.9 | 236.7 ± 219.6 | 0.89 |
| CD62E+ EV/ml | 304.2 ± 121.7 | 449.1 ± 123.0 | 0.56 |
| CD235a+ EV/ml | 29,281 ± 5,687 | 42,353 ± 14,021 | 0.33 |
| CD61+ EV [%] | 19.0 ± 4.7 | 7.0 ± 1.8 | 0.21 |
| Caveolin-3+ EV [%] | 5.0 ± 0.9 | 9.8 ± 4.7 | 0.11 |
| CD45+ EV [%] | 1.1 ± 1.0 | 0.3 ± 0.2 | 0.68 |
| CD62E+ EV [%] | 0.6 ± 0.2 | 0.7 ± 0.2 | 0.84 |
| CD235a+ EV [%] | 53.8 ± 5.3 | 52.8 ± 12.2 | 0.93 |
CD61+ (platelet) EV, caveolin-3+ (cardiomyocyte) EV, CD45+ (leukocyte) EV, CD62E+ (endothelial) EV, CD235a+ (erythrocyte) EV. LVEF was obtained from the first echocardiography performed by a specialist after STEMI, usually 2-4 days after the event. Data are presented as mean±SEM. p-values were calculated by an unpaired Student's t-test. Significant p-values are indicated in bold.