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. 2021 Nov 4;12:735530. doi: 10.3389/fphar.2021.735530

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Copyright © 2021 Jiang, Dong, Zhai, Lou, Jin, Cheng, Chen, Guo, Lin, Ding and Gao.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Paeoniflorin (PF) promoted cell function in TBHP-treated HUVECs. (A,D) Evaluation of PF-mediated HUVEC neovascularization using tube formation assay (scale bar, 100 μm). (B,E) Assessment of PF-mediated HUVEC migration using the transwell system (scale bar, 100 μm). (C,F) Evaluation of PF-mediated HUVEC adhesion using cell-matrix adhesion assay (scale bar, 100 μm). Data: mean ± SD, *p < 0.05 and **p < 0.01. n = 3.