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. Author manuscript; available in PMC: 2022 Sep 10.
Published in final edited form as: J Control Release. 2021 Jul 16;337:179–192. doi: 10.1016/j.jconrel.2021.07.018

Figure 6. Systemic biodistribution of sugar-conjugated dendrimers compared to unmodified dendrimers.

Figure 6.

Glioblastoma bearing mice were injected with unmodified (D-OH), glucose- (D-GLU), mannose- (D-MAN), and galactose-conjugated (D-GAL) dendrimers on day 14 after tumor inoculation. All dendrimers rapidly clear from the body, with less than 1% of the initial injected dose remaining per mL of plasma after 24 hours. Conjugation with sugars alters systemic biodistribution. * p < 0.05, ** p < 0.01, *** p < 0.001.