Table 2.
Sources of Human B-cells
| Cell type | Source | Description |
|---|---|---|
| Primary cells | ||
| Primary B-cell EBV- | New England Organ Bank | Human spleen |
| B-LCL | ||
| Newly EBV-infected primary B-cell | In vitro infection with B95-8 virus strain | Human spleen |
| Standard B-lymphoblastoid cell line | ||
| B95-8 | ATCC-CRL-1612 | Marmoset B-cells, immortalized with the prototype B95-8 EBV strain |
| EBV + Burkitt lymphoma lines | ||
| P3HR1 | ATCC-HTB-62 | Burkitt lymphoma derived from Jijoye Burkitt lymphoma |
| Daudi | ATCC-CCL-213 | Burkitt lymphoma |
| Raji | ATCC-CCL-86 | Burkitt lymphoma |
| EBV-Burkitt lymphoma lines | ||
| Ramos | ATCC CRL-1596 | Burkitt lymphoma |
| BL41 | ATCC-ACC160 | Burkitt lymphoma |
| In vitro-infected EBV + Burkitt’s lymphoma lines | ||
| Ramos/B95-8 | Fred Wang and Elliot Kieff Harvard University | In vitro EBV-infected Burkitt lymphoma line |
| BL41/B95-8 | Fred Wang and Elliot Kieff Harvard University | In vitro EBV-infected Burkitt lymphoma line |
Cell lines included two EBV−, five EBV+ Burkitt lymphoma lines, and two EBV-immortalized lymphoblastoid cell lines (LCLs), as well as primary B-cells
ATCC American Type Culture Collection (Manassas, Virginia)