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. 2021 Nov 18;29:161. doi: 10.1186/s13049-021-00978-z

Table 2.

Dosages and frequencies of administration of potent analgesics

n (%) or median (IQR) p
Age [yrs] 0–5
n = 443
6–10
n = 902
11–14
n = 1540
Fentanyl
n total 117 (26.4) 268 (29.7) 496 (32.2) 0.053
Proportion with documented dosage 55 (47.0) 166 (61.9) 270 (48.0)
Dosage [mg] 0.05 (0.03–0.07) 0.05 (0.05–0.10) 0.10 (0.05–0.20) < 0.001
Piritramide
n total 46 (10.4) 210 (23.3) 462 (30.0) < 0.001
Proportion with documented dosage 26 (56.5) 140 (66.7) 299 (64.7)
Dosage [mg] 2.38 (1.50–3.94) 4.00 (3.00–7.50) 7.50 (3.75–7.50) < 0.001
Morphine
n total 1 (0.2) 12 (0.1) 14 (0.9) 0.140
Proportion with documented dosage 1 (100.0) 6 (50.0) 10 (71.4)
Dosage [mg] 1.5 4.00 (4.00–5.00) 5.00 (3.50–6.00) 0.251
Esketamine
n total 293 (66.1) 487 (54.0) 744 (48.3) < 0.001
Proportion with documented dosage 156 (53.2) 258 (53.0) 325 (43.7)
Dosage [mg] 15.0 (10.0–25.0) 15.0 (12.5–25.0) 20.0 (15.0–25.0) < 0.001

IQR denotes interquartile range