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. 2021 Nov 18;19:329. doi: 10.1186/s12957-021-02440-x

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 8 — The effect of CXCL10 on cellular immunity and angiogenesis. A The expression of CXCL10 mRNA in each treatment group. B, C The cell viability and apoptosis in each treatment group. D Cell viability and apoptosis in each treatment group. E An in vitro Matrigel tube formation assay was performed to evaluate the angiogenic effect of CXCL10, and representative micrographs images are shown at × 200. The number of branches were analyzed, and the data represent the means ± SEM of triplicates. F MRNA and protein expression of angiogenesis markers (VEGFA, COX2, and CD34) in different treatments. NC normal control group, si-NC inhibitor control group, si-CXCL10 suppress CXCL10 expression group, CXCL10 overexpression CXCL10 group, *p < 0.05 vs. NC group