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. Author manuscript; available in PMC: 2021 Nov 18.
Published in final edited form as: Cell Rep. 2021 Nov 2;37(5):109910. doi: 10.1016/j.celrep.2021.109910

Figure 3. RBFOX2-regulated tandem APA modulates 3′UTR length and affects mRNA levels.

Figure 3.

(A) The number of genes that undergo tandem APA changes generating shorter or longer 3′UTRs in RBFOX2 KD H9c2 myoblasts.

(B) Enrichr TargetScan analysis of genes that display 3′UTR length changes upon RBFOX2 depletion revealed known microRNA binding sites within the majority of these genes.

(C) Gene expression changes in RBFOX2 KD H9c2 myoblasts.

(D) GO analysis of genes that are downregulated in RBFOX2-depleted H9c2 myoblasts.

(E) The number of genes that exhibit both APA and gene expression changes in RBFOX2 KD H9c2 myoblasts.