Table 3.
Mean peak height (PH) of significantly different metabolites in X-deletion (n = 3) compared to control samples (n = 3) and their ratio (ID methods: 1 = m/z match to internal library, 2 = retention time match to internal library).
| Metabolite Name | m/z | Ion/Adduct | ID methods | Mass Accuracy (ppm) | Average X-deletion PH (n = 3) | X-deletion RSD (%) | Average Control PH (n = 3) | Control RSD (%) | X-deletion/ Control |
|---|---|---|---|---|---|---|---|---|---|
| Glutamine (NEG) | 145.0618 | [M−H]− | 1,2 | 3.5 | 2.61E+06 | 9.69 | 5.91E+04 | 86.62 | 44.2 |
| Dihydroxyacetone Phosphate (NEG) | 168.9905 | [M−H]− | 1,2 | 1.5 | 1.15E+06 | 15.03 | 3.81E+04 | 55.32 | 30.1 |
| Phosphocholine (POS) | 184.0735 | [M+H]+ | 1,2 | -1.8 | 5.83E+07 | 0.76 | 3.26E+06 | 4.69 | 17.9 |
| 6-Phosphogluconic Acid (NEG) | 275.0178 | [M−H]− | 1,2 | 3.7 | 1.31E+05 | 20.3 | 8.70E+03 | 89.98 | 15 |
| Ribulose 5-Phosphate (POS) | 253.0084 | [M+H]+ | 1,2 | 0 | 2.32E+05 | 5.24 | 1.62E+04 | 27 | 14.3 |
| D-Ribose 5-Phosphate (NEG) | 229.0112 | [M−H]− | 1,2 | -0.7 | 1.80E+06 | 4.18 | 1.63E+05 | 18.87 | 11 |
| Arachidonic Acid (20:4) (NEG) | 303.2329 | [M−H]− | 1,2 | 1.7 | 9.75E+05 | 70.8 | 9.12E+04 | 107.06 | 10.7 |
| 2-Aminoethyl Dihydrogen Phosphate (NEG) | 140.0119 | [M−H]− | 1,2 | 4.7 | 2.59E+06 | 4.69 | 2.89E+05 | 87.32 | 9 |
| Docosahexaenoic Acid (22:6) (NEG) | 327.233 | [M−H]− | 1,2 | 1.7 | 1.41E+05 | 70.73 | 1.58E+04 | 120.27 | 9 |
| CMP (NEG) | 322.0443 | [M−H]− | 1,2 | 1 | 9.20E+05 | 22.02 | 1.18E+05 | 86.68 | 7.8 |
| Ethanolamine Phosphate (POS) | 142.0263 | [M+H]+ | 1,2 | 4.3 | 8.09E+06 | 5.97 | 1.06E+06 | 3.72 | 7.6 |
| Ascorbic Acid (NEG) | 173.0085 | [M−H]− | 1,2 | -0.7 | 3.06E+04 | 19.81 | 2.22E+05 | 67.11 | 7.3 |