Table 2.
Incidence of herpes zoster per 100 000 person-years by baseline characteristics and RZV status from 2018 to 2019
| Unvaccinated | Vaccinated | ||||||
|---|---|---|---|---|---|---|---|
| Number of cases | Number of Person-Years | Incidence rate (95%CI) | Number of cases | Number of Person-Years | Incidence rate (95% CI) | Rate Ratioa (95% CI) | |
| Overall | 1273 | 119719 | 1063.3 (1006, 1122.8) | 27 | 8291 | 325.6 (217.7, 464.4) | 0.31 (0.21,0.45) |
| Age group | |||||||
| 50–59 | 467 | 49449 | 944.4 (861.3,1032.7) | 0 | 196 | 0 | 0 |
| 60–69 | 442 | 42592 | 1037.7 (944, 1137.5) | 4 | 717 | 557. 7 (173.1, 1295.3) | 0.54 (0.2,1.44) |
| 70–79 | 214 | 17914 | 1194.6 (1041.6, 1361.9) | 13 | 4537 | 286.5 (157.6, 471.7) | 0.24 (0.14,0.42) |
| 80+ | 150 | 9764 | 1536.2 (1303.3, 1795.4) | 10 | 2841 | 352.0 (176.4, 617.3) | 0.23 (0.12,0.43) |
| Sex | |||||||
| Female | 740 | 61386 | 1205.5 (1120.7, 1294.4) | 19 | 4492 | 423.0 (260.1, 642.6) | 0.35 (0.22,0.55) |
| Male | 533 | 58334 | 913.7 (838.3, 993.5) | 8 | 3799 | 210.6 (96.2, 391.9) | 0.23 (0.11,0.46) |
| Race | |||||||
| Asian | 534 | 45147 | 1182.8 (1085.3,1286) | 12 | 4107 | 292.2 (156.4, 490) | 0.25 (0.14,0.44) |
| White | 347 | 34475 | 1006.5 (904.3, 1116.2) | 7 | 2266 | 308.9 (132.7, 597.3) | 0.31 (0.15,0.65) |
| More Than One Race | 199 | 19273 | 1032.5 (895.6, 1182.7) | 8 | 1247 | 641.8 (293.3, 1194.5) | 0.62 (0.31,1.26) |
| Native Hawaiian/Other Pacific Islander | 110 | 10525 | 1045.1 (861.8, 1252.8) | 0 | 420 | 0 | 0 |
| Black | 8 | 1056 | 757.4 (346.1, 1409.7) | 0 | 37 | 0 | 0 |
| American Indian/Alaska Native | 6 | 282 | 2125.8 (844.8, 4307.2) | 0 | 8 | 0 | 0 |
| Unknownb | 69 | 8960 | 770.1 (602.4, 966.4) | 0 | 207 | 0 | 0 |
| Ethnicity | |||||||
| Non-Hispanic | 1161 | 108059 | 1074.4 (1013.8, 1137.4) | 27 | 7922 | 340.8 (227.9, 486) | 0.32 (0.22,0.46) |
| Hispanic | 66 | 5237 | 1260.3 (980.2, 1589.3) | 0 | 251 | 0 | 0 |
| Unknownc | 46 | 6424 | 716.1 (528.6, 943.4) | 0 | 118 | 0 | 0 |
| Prior ZVL vaccination within one year of index date | |||||||
| Yes | 26 | 3695 | 703.6 (466.6, 1009.7) | 1 | 184 | 543.8 (31, 2392.2) | 0.77 (0.1,5.7) |
| No | 1247 | 116024 | 1074.8 (1016.2, 1135.5) | 26 | 8107 | 320.7 (212.7, 460.2) | 0.3 (0.2,0.44) |
a
Rate ratio was computed as incidence rate in vaccinated group/incidence rate in unvaccinated group.
b
The unknown race category includes individuals with either unknown or missing race.
c
The unknown ethnicity category includes individuals with either unknown or missing ethnicity