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. Author manuscript; available in PMC: 2022 Jun 29.
Published in final edited form as: Vaccine. 2021 Jun 8;39(29):3974–3982. doi: 10.1016/j.vaccine.2021.05.056

Table 4.

Unadjusted and adjusted vaccine effectiveness of RZV by subgroups from 2018 to 2019

Unadjusted VE point estimate (95%CI) Adjusted VE point estimate (95%CI)
Overall a
73.8 (60.7, 82.5) 83.5 (74.9, 89.2)
Age group b
50–59 100 100
60–69 48.0 (- 40.7, 80.8) 67.7 (11.8, 88.1)
70–79 73.0 (51.8, 84.9) 83.3 (70.1, 90.7)
80+ 78.3 (58.1, 88.8) 86.4 (73.5, 93.0)
Sex
Female 68.5 (48.5, 80.8) 79.5 (66.0, 87.7)
Male 80.6 (60.8, 90.4) 89.3 (77.9, 94.8)
Race c
Asian 80.0 (63.8, 89.0) 88.1 (77.5, 93.7)
White 73.7 (39.6, 88.5) 82.0 (58.4, 92.2)
Multiple 17.9 (- 81.4, 62.9) 43.7 (- 22.2, 74.0)
Native Hawaiian/Other Pacific Islander 100 100
American Indian/Alaska Native 100 100
Black 100 100
Unknown 100 100
Ethnicity d
Hispanic 100 100
Non-Hispanic 72.4 (58.6, 81.6) 82.7 (73.6, 88.7)
Unknown 100 100
Prior ZVL
Yes_ZVL 18.9 (- 309.4, 83.9) 61.1 (- 124.9, 93.3)
No_ZVL 74.4 (61.3, 83.0) 83.9 (75.2, 89.5)
a

Values are reported as %.

b

RZV effectiveness confidence intervals could not be computed for the age subgroup 50–59 due to zero reported HZ cases in the vaccinated cohort.

c

RZV effectiveness confidence intervals could not be computed for Native Hawaiian/Other Pacific Islander, American Indian/Alaska Native, Black, and Unknown racial subgroups due to zero reported cases of HZ in the vaccinated cohorts.

d

RZV effectiveness confidence intervals could not be computed for Hispanic and unknown ethnic subgroups due to zero reported cases of HZ in the vaccinated cohorts.