Table 1.
Characteristics of localized patients with FOXO1 fusion positive status (n=269).
| Characteristic | N (%) |
|---|---|
| Study | |
| D9602 | 13 (4.8) |
| D9803 | 115 (42.8) |
| ARST0531 | 141 (52.4) |
| Sex | |
| Male | 139 (51.7) |
| Female | 130 (48.3) |
| Age | |
| <1 | 17 (6.3) |
| 1-9 | 118 (43.9) |
| 10+ | 134 (49.8) |
| Primary tumor site | |
| Bladder/prostate | 3 (1.1) |
| Extremity | 81 (30.1) |
| Genitourinary, non-bladder/prostate* | 4 (1.5) |
| Head and neck* | 31 (11.5) |
| Intrathoracic | 1 (0.4) |
| Orbit* | 14 (5.2) |
| Parameningeal | 92 (34.2) |
| Perineum/anus | 13 (4.8) |
| Retroperitoneum | 8 (3.0) |
| Trunk | 19 (7.1) |
| Other | 3 (1.1) |
| Tumor size | |
| ≤5 cm | 158 (58.7) |
| >5 cm | 108 (40.1) |
| Unknown | 3 (1.1) |
| Nodal | |
| No, N0 | 181 (67.3) |
| Yes, N1 | 87 (32.3) |
| Unknown | 1 (0.4) |
| Invasiveness (T status) | |
| T1 | 146 (54.3) |
| T2 | 123 (45.7) |
| Group | |
| I | 17 (6.3) |
| II | 66 (24.5) |
| III | 186 (69.1) |
| Histology | |
| Alveolar rhabdomyosarcoma | 257 (95.5) |
| Embryonal rhabdomyosarcoma | 1 (0.4) |
| Not otherwise specified | 5 (1.9) |
| Mixed rhabdomyosarcoma | 6 (2.2) |
| FOXO1 fusion partner | |
| PAX3 | 192 (71.4) |
| PAX7 | 51 (19) |
| Unknown | 26 (9.7) |
*
Favorable site