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. 2021 Nov 15;9:e12290. doi: 10.7717/peerj.12290

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© 2021 Liu et al.

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, reproduction and adaptation in any medium and for any purpose provided that it is properly attributed. For attribution, the original author(s), title, publication source (PeerJ) and either DOI or URL of the article must be cited.

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For Nora virus, ORF1 is a highly charged protein of unknown function; ORF2 has helicase, protease and RdRP domains; ORF3 encodes a protein of unknown function; ORF4 encodes structural proteins. The BuGV2 ORF1 has homology to Nora virus ORF2 only. While BuGV2 has two dicistrovirus domains, the encoded protein does not show homology to other viral sequences.