Fig. 2.

The series of engineered strains and their production of Ehrlich metabolites (in mg l⁻¹) when cultured for 5 days in YNB medium containing 10 g l⁻¹ of glucose. The strains’ genotypes are indicated by the green boxes located below the strains’ names. The mutated forms of Aro4 (YlAro4^K221L) and Aro7 (YlAro7^G139S) were equivalent to the feedback‐inhibited forms of the enzymes in S. cerevisiae (ScAro4^K229L and ScAro7^G141S). WT: wild‐type strain; 2‐4OHPE: 2‐(4‐hydroxyphenyl) ethanol; 4OHPAA: 4‐hydroxyphenylacetic acid; 2PE: phenylethanol; and PAA: phenylacetic acid.