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. 2021 Nov 19;100(46):e27593. doi: 10.1097/MD.0000000000027593

Table 4.

Multivariate subgroup analysis by different baseline characteristics for the association between cirrhosis status and hospital mortality.

No Cirrhosis N = 2331 Cirrhosis N = 322 OR (95% CI) P-value P value for interaction
Gender
 Male 1342 (32.7) 159 (63.6) 2.27 (1.67–3.08) <.0001 .73
 Female 989 (30.0) 163 (66.0) 2.82 (2.06–3.87) <.0001
Age
 <50 382 (20.7) 41 (59.4) 2.04 (1.11–3.74) .021 .81
 >50 1949 (35.1) 281 (65.6) 2.44 (1.92–3.09) <.0001
Diabetes
  No 1140 (30.1) 184 (68.9) 2.81 (2.06–3.82) <.0001 .14
  Yes 1191 (33.1) 138 (60.0) 2.04 (1.49–2.80) <.0001
Mechanical ventilation
 No 408 (14.4) 52 (37.9) 2.49 (1.70–3.64) <.0001 .76
 Yes 1923 (42.2) 270 (75.0) 2.31 (1.77–3.02) <.0001
Vasopressors
 No 921 (21.8) 97 (52.2) 2.60 (1.86–3.64) <.0001 .5
 Yes 1410 (44.6) 225 (72.4) 2.32 (1.74–3.10) <.0001
Chronic cardiac disease
 No 1609 (29.9) 279 (66.4) 2.36 (1.84–3.04) <.0001 .14
 Yes 722 (35.8) 43 (55.8) 1.70 (1.01–2.86) .0432
Chronic respiratory disease
 No 1737 (32.5) 258 (64.2) 2.13 (1.65–2.73) <.0001 .33
 Yes 594 (28.9) 64 (67.4) 3.05 (1.86–4.99) <.0001
Lactic acid
 <2mmol/L 1225 (26.4) 98 (55.7) 2.63 (1.87–3.69) <.0001 .81
 >2mmol/L 1106 (40.2) 224 (69.8) 2.25 (1.68–3.01) <.0001
Hemodialysis
 No 1944 (29.7) 258 (63.4) 2.38 (1.86–3.04) <.0001 .44
 Yes 387 (45.9) 64 (71.1) 2.10 (1.25–3.54) <.0001