Figure 1.

Differentially expressed genes in 3 data sets and confirmation of integrated differentially expressed genes in terms of gene expression profiling. (A) Volcano plot and heatmap of differentially expressed RNAs in the GSE60399, GSE94916 and GSE102915 data set. In Volcano plot, the red, green and black dots represent genes that are upregulated, downregulated and not significantly differentially expressed, respectively. In heatmap, upregulated genes are shown in red, and downregulated genes are shown in blue; the rows represent discovered RNAs in dataset, the columns represent samples. (B) Venn diagram of the upregulated and downregulated genes in the GSE60399 and GSE94916 data sets. GSE60399 is shown in blue, GSE94916 is shown in red.