Table 1.

Integrated differentially expressed genes in COPD.

DEGs	Gene names
Upregulated	SLC25A37, CEACAM6, ANXA3, DEFA4, TMEM45A, ORM1, MCEMP1, HP, HPR, MPO, ARG1, IGFBP2, CAMP, AQP1, BPI, CA1
Downregulated	LMAN1, LOC93622, MRPL1, BCL2, CD6, RHOH, ATP10A, NDRG2, HLA-DOA, TAF9, METTL5, THOC7, KLRG1, ITK, PTPN4, MYC, ZNF18, NELL2, FARS2, PDCD6, ANKH, TRIM4, CHD2, LAT, CD28, OBFC1, TMEM50B, SNAPC5, TRAF3IP3, CD8B, TBRG1, TCF20, LY9, USP39, PASK, TRIM5, ABLIM1, RPP38, KLRB1, ZAP70, PTPRCAP, IL12RB1, ID3, PNPLA4, RPS23, ZNF669, PGRMC2, PLEKHB1, BTN3A2, APBB1, NIPSNAP1, MAL, LEF1, TTC24, DDX26B, MRFAP1L1, MAN1C1, RUVBL1, MAD1L1, C1orf52, NMT2, MLLT3, CNOT10, ZNF184, ATG9B, IVD, UBASH3A, CLK1, GIMAP2, SIGIRR, TIMM9, GTF2F1, COPS8, SNRPN, CD48, TNRC6C, CD3G, IL7R, CD96, TIMM44, ZFR, TCF7, GMDS, ZNF579, KLHL3, PINX1, SCML4, CD40 LG, CYCS, AES, MTMR1, RIOK1, EXOSC2, POLR1E, LDHB, NUP88, PIGP, FXN, IL27RA, FAIM3, ASTE1, P2RY8, PEX26, CNOT7, ARHGAP12, PRKACB, THEM4, BCL11B, GPR18, TNFRSF25, CCR7, BIN1, BUB3, PPP1R13 L, GATA3, LDLRAP1, SYNCRIP, PIGY, BZW2, AK5, CUTC, CD22, LPIN1, CYFIP2, SATB1, LETMD1, CD1C, FBXL12, TOMM20, NOSIP, GPX7, FLT3 LG, RPA2, RPS4X, RPS27A, GZMK, CDK6, LCK, KLRK1, P2RX5, CD248, LTB, CD7, XRRA1, AGPAT4, PYHIN1, ZNF101, CD3D, TBP, DPH5, EBAG9, CD244, RORA, TBCC, ACADSB, CDK5RAP1, PLD4, PRKY, ITM2A, CD5, PORCN, RNF157, HKDC1, DENND2D, RPS6KB1

COPD = chronic obstructive pulmonary disease, DEGs = differentially expressed genes.