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. 2021 Nov 19;100(46):e27860. doi: 10.1097/MD.0000000000027860

Table 2.

Comparison of the NIHSS, ADL, mRS and HAMA, HAMD at different time points in 2 groups.

Experimental group (N = 94) Control group (N = 77) P value
Primary outcomes
ADL
 Before treatment 34.36 ± 6.402 33.51 ± 5.853 .368
 On the days 14 53.72 ± 8.948 49.48 ± 7.805 .001
 On the months 3 67.45 ± 12.109 58.64 ± 9.306 <.001
 On the months 6 85.85 ± 10.540 80.13 ± 13.002 .002
mRS
 Before treatment 3.98 ± 0.145 3.96 ± 0.195 .498
 On the days 14 3.22 ± 0.571 3.40 ± 0.494 .031
 On the months 3 2.64 ± 0.526 3.06 ± 0.439 <.001
 On the months 6 1.57 ± 1.042 1.99 ± 0.803 .005
Secondary outcomes
NIHSS
 Before treatment 17.07 ± 2.263 17.10 ± 2.326 .934
 On the days 14 11.90 ± 2.379 12.73 ± 2.315 .024
 On the month 1 6.59 ± 3.244 7.65 ± 3.417 .039
HAMA
 On the months 3 15 (16.0%) 26 (33.8%) .007
 On the months 6 17 (18.1%) 29 (37.7%) .005
HAMD
 On the months 3 9 (9.6%) 19 (24.7%) .012
 On the months 6 14 (14.9%) 25 (32.5%) .010
Safety outcomes
 Primary intracranial hemorrhage 0 0
 Gastrointestinal hemorrhage 2 (2.1%) 3 (3.9%) .659
 Nasal and gum bleeding 5 (5.3%) 4 (5.2%) 1.000
 Subcutaneous hemorrhage 0 0

ADL = Barthel Index of activities of daily living, HAMA = Hamilton Anxiety Scale, HAMD = Hamilton Depression Scale, mRS = Modified Rankin Scale, NIHSS = National Institutes of Health Stroke Scale.