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. 2021 Sep 13;39(33):3693–3704. doi: 10.1200/JCO.21.01436

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© 2021 by American Society of Clinical Oncology

Licensed under the Creative Commons Attribution 4.0 License: http://creativecommons.org/licenses/by/4.0/

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FIG 3. — Kaplan-Meier curve for OS in FOCUS4-N. Cox regression HR, adjusted for minimization factors = 0.93 (95% CI, 0.69 to 1.27), P = .66. Minimization factors: location of primary tumor (left, right, and rectum); baseline WHO performance status; baseline disease assessment; No. of metastases; first-line therapy (fluoropyrimidine, oxaliplatin or irinotecan, and monoclonal antibody); and biomarker cohort, stratified for FOCUS4 trial timepoints. AM, active monitoring; HR, hazard ratio; OS, overall survival.